Saturday, March 7, 2026

"Human Brain Cells Learn to Play Doom in Cortical Labs Experiment"

From Decrypt, March 2:

Living human neurons were trained to play Doom, extending the long-running engineering benchmark into biological computing. 

  • Cortical Labs connected 200,000 human neurons to Doom using electrical stimulation and software controls.
  • The cells can navigate and shoot, but currently plays like beginners.
  • The experiment joins a long list of unusual platforms used to run the classic game.

The "Can it run Doom?" challenge just crossed its next frontier.

Melbourne, Australia-based startup Cortical Labs has successfully trained clusters of living human brain cells to navigate the 1993 classic video game.

In a video posted on YouTube last week, researchers connected living human neurons to software that converts gameplay into electrical signals and translates neural activity into in-game controls, allowing the cells to move, react to enemies, and fire weapons.

“In 2021, we got Pong working on the neurons. That was sort of like a first kind of test to see if we can have some kind of cool game that speaks to the people. But then the number one response we got is, can it run Doom?” Alon Loeffler, an application scientist at Cortical Labs, told Decrypt....

....MUCH MORE