Saturday, June 5, 2021

Bill Gates and the NextGen FutureCow

Back in 2014 I realized I was not a wordsmith:

The White House Is Searching for the NextGen Futurecow (MOO)
Nextgen futurecow is probably as close to a neologism as I'm ever going to get....
(cue deep mournful lowing)

Nope, not a Shakespeare with his 422 brand-spanking-new words and the 1300 other words he raised from obscurity. So it goes. (cue deep mournful lowing)
From Wired UK, May 25:

The hunt for the master cow that will feed the world

Researchers are racing to find the cow cells that will make up tomorrow’s burgers, but in the secretive world of cultured meat, no one wants to share

LAURA DOMIGAN IS a chronicler of cows. Every biographical detail and pharmacological footnote could be crucial, so the biochemist has a long list of questions for the farmers she works with. Where was the cow raised? What did it eat? What did it look like? Which medicines did it take and why? How old was the cow when it was slaughtered?
Domigan knows enough to write a family history about these cows, but she’s more interested in what they leave behind when they die. Shortly after a cow has been slaughtered, one of her colleagues arrives at the abattoir with a Petri dish in hand and removes a tiny slither of muscle tissue from the carcass, bathing it in a salt solution to stop the cells within from bursting open or shrivelling up. The precious nugget is then packed in ice and ferried back to Domigan’s laboratory at the University of Auckland in New Zealand.
This is where the bovine biographies come in handy. Domigan’s job is to work out how to turn that collection of cells into hunks of meat grown in stainless steel bioreactors. From a Petri dish to a silo full of steaks, the hope is that one day this process can replace some of the 1.5 billion crop-guzzling, methane-burping cows on the planet today. At a glance, the formula for cultured – or lab-grown – meat is simple. Take some animal cells, feed them on a nutrient-filled broth so they duplicate lots of times, then alter that broth slightly so the cells turn into the constituent parts of meat: muscle, fat, and connective tissue. Perfect this recipe and we could – theoretically – satiate the entire planet’s hunger for burgers and steaks with cells taken from a single cow.
Getting those cells right is a make-or-break issue for the cultured meat industry. Start with the wrong cells and your vat full of would-be-burgers can very quickly turn into a sludge of proto-meat soup. Solve that problem and you’ve still got to work out how to grow those cells at a cost close to conventional meat and then build a whole production process to reliably brew up thousands of tonnes of meat a year. Distilling the essence of an animal into a slice of cells no bigger than a fingertip is a colossal challenge. So far, no one has managed to crack it.
For companies and academics, the only way of figuring all this out is to get up close and personal with a lot of cells. This means getting their hands on cell lines: reliable, well-studied and easy-to-access cells that anyone can experiment on. Cell lines are one of the most basic building tools in scientific research – in the biomedical industry, they’re absolutely everywhere. In the world of cultured meat, however, these much-needed cell lines either don’t exist or are locked up in the labs of a handful of cultured meat companies.
Some scientists fear that the lack of access to cell lines is holding the entire cultured meat industry back. The cellular blueprint for tomorrow’s factory-brewed burgers is out there somewhere – but, without access to cell lines, many of the people trying to make this future a reality are still fumbling around in the half-shadows.
THE LARGEST COLLECTION of cell lines in the world is in Manassas, Virginia. There, tucked safely away in a series of freezers, the headquarters of the American Type Culture Collection (ATCC) houses nearly 4,000 cell lines from over 150 species. For more than half-a-century, these cells have been the starting point for the development of vaccines, drugs and for the study of cancers and genes. Trace the history of any biomedical breakthrough back far enough and you will probably find a scientist reaching into a freezer to extract a vial of cells shipped from a collection like the ATCC....

And Mr. Gates?

He has extensive interests in the faux meat market:

Aug. 27
Bill Gates Invests In Another Lab-Grown Meat Company
August 2
"Bill Gates headlines an all-star list of investors pumping $75 million into meatless burgers" 
Mr. Gates also partnered with Li Ka-Shing and Khosla on Hampton Creek which is attempting to pivot from Just Mayo into laboratory-grown 'meat'.*

As well as investments in real cows:
Bill Gates’ investment in 'super cows' shows that many of the world’s farms are in crisis mode
"If you care about the poor, you should care about agriculture. And if you care about agriculture, you care about livestock," he told an audience at the University of Edinburgh. "What that means in this context is helping poor farmers get as much as possible out of their animals."
And if I were a betting man I'd bet that the two strains of investment have already met and intermingled.