Sunday, June 22, 2025

People With Severe Type 1 Diabetes Apparently Cured

From the Hartford Courant, June 21:

People with severe diabetes are cured in small trial of new drug
About 2 million Americans have Type 1 diabetes 

A single infusion of a stem cell-based treatment may have cured 10 out of 12 people with the most severe form of Type 1 diabetes. One year later, these 10 patients no longer need insulin. The other two patients need much lower doses.

The experimental treatment, called zimislecel and made by Vertex Pharmaceuticals of Boston, involves stem cells that scientists prodded to turn into pancreatic islet cells, which regulate blood glucose levels. The new islet cells were infused and reached the pancreas, where they took up residence.

The study was presented Friday evening at the annual meeting of the American Diabetes Association and published online by The New England Journal of Medicine.

“It’s trailblazing work,” said Dr. Mark Anderson, professor and director of the diabetes center at the University of California, San Francisco....

....MUCH MORE